Systematic review follows a preset protocol. They aim to identify all evidence relating to a carefully considered research question. The research question informs what will be included and excluded from the review. The evidence is then gathered, the results extracted, and each study is appraised for quality or risk of bias. The conclusions are based on the quality of the evidence. Importantly systematic reviews are transparent and reproducible.
Systematic review is the methodology underpinning all evidence based decision making. It avoids bias and opinion.
Using this technique, we provide a transparent summary of the whole evidence base and identify the best evidence; enabling the client to make informed decisions.
Systematic reviews take 3 -12 months to perform.
The following steps are followed in consultation with the client:
1 Formulate the research question and the inclusion and exclusion criteria
2 Search and identify all evidence
3 Extract data and make assessments (in-house validity tools or published risk of bias tools)
4 Provide layered evidence: evidence table backed by detailed data and decisions
5 Draw conclusions/ recommendations
We specialise in systematic reviews of early stage preclinical studies. We have the expertise in a range of technologies and proprietory tools to assess marker and model validity.