Anne has a background in cancer research. Her area of expertise includes cancer stem cells (her research group was the first to identify and isolate prostate cancer stem cells) and patient-derived cancer models (primary culture, organoids, PDX). More recent interests include the use of systematic review methodology to tackle the reproducibility crisis in biomedical research

Shona has spent 8 years working in clinical epidemiology preparing systematic reviews, meta-analyses, rapid reviews, and health technology assessments to support policy making, licensing and reimbursement decisions in clinical research. Previous to this, she was a Wellcome Fellow in cancer research and tissue development. Her focus was alternative models to animal testing (human tissue culture, organoids, 3D models and stem cells)


Our team has unique expertise in systematic reviews and critical appraisal combined with a deep understanding of biomedical science. This combination ensures we can bring expertise from both fields to enable a more insightful critique of research findings

We specialise in human cell models and their application in drug testing and precision medicine. Using our well-defined tools and methodology we provide an unbiased, non-technical top-line summary of the evidence with a clear idea of the strengths and weaknesses to aid decision making

Our mission is to increase the success of biomedical translation using the principles of systematic review and open science

QED Biomedical supports open science, the reproducibility project and the improvement of reporting in scientific journals. We advocate the submission of protocols and the publication of negative results to prevent publication bias and waste of laboratory resources. We are interested in the development of tools and checklists to better critique the applicability of bench science to the clinic